Basic information of RPS6KB1 :
| Official Symbol of Gene | RPS6KB1 |
| Species | Homo sapiens |
| Entrez Gene ID | 6198 |
| Official Full Name | ribosomal protein S6 kinase B1 |
| Also known as | S6K; PS6K; S6K1; STK14A; p70-S6K; p70 S6KA; p70-alpha; S6K-beta-1; p70(S6K)-alpha |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000108443 MIM:608938; AllianceGenome:HGNC:10436 |
| Map Location | 17q23.1 |
| Variation Type | SNP |
| refSNP ID | rs180515 AG |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | N/A |
| Detected Method | PCR-RFLP |
| Disease | MS |
| Disease subtype | N/A |
| Population | Iranian |
| Sample Size | 130 patients with MS and 128 matched healthy controls |
Literature information of multiple sclerosis :
| Pubmed ID | 28079472 |
| Year | 2017 |
| Title | Polymorphisms of RPS6KB1 and CD86 associates with susceptibility to multiple sclerosis in Iranian population |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | For this variation, AA genotype was shown to have protective effect (P = 0.016 and OR = 0.6), while GG genotype was a susceptive genotype to MS (P = 0.04 and OR = 2.2). |
| Mechanism/Pathway | encodes p70S6K1 protein |
