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Basic information of CD86 :

Official Symbol of Gene CD86
Species Homo sapiens
Entrez Gene ID 942
Official Full Name CD86 molecule
Also known as B70; B7-2; B7.2; LAB72; CD28LG2
Gene Type protein coding
dbXrefs Ensembl:ENSG00000114013 MIM:601020; AllianceGenome:HGNC:1705
Map Location 3q13.33
Variation Type SNP
refSNP ID rs9282641 GG

Sample information of multiple sclerosis:

Detected Sample blood
Sample Detail N/A
Detected Method PCR-RFLP
Disease MS
Disease subtype N/A
Population Iranian
Sample Size 130 patients with MS and 128 matched healthy controls

Literature information of multiple sclerosis :

Pubmed ID 28079472
Year 2017
Title Polymorphisms of RPS6KB1 and CD86 associates with susceptibility to multiple sclerosis in Iranian population

Results of multiple sclerosis :

Risk Type Disease risk
Main Result Positive
Result For this SNP, AG genotype had predisposing effect (P = 0.04, OR = 2.3), and GG genotype showed protective (P = 0.01, OR = 0.411).
Mechanism/Pathway CD86 gene codes a membrane protein type I