Home Details
| Official Symbol of Gene | IFNG |
| Species | Homo sapiens |
| Entrez Gene ID | 3458 |
| Official Full Name | interferon gamma |
| Also known as | IFG; IFI; IMD69 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000111537 MIM:147570; AllianceGenome:HGNC:5438 |
| Map Location | 12q15 |
| Variation Type | marker |
| refSNP ID | D12S375 |
| Detected Sample | blood |
| Sample Detail | venous blood |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | Sardinians |
| Sample Size | 217 simplex families(ie one affected sib, two healthy parents |
| Pubmed ID | 12486605 |
| Year | 2002 |
| Title | Linkage disequilibrium analysis of chromosome 12q14-15 in multiple sclerosis: delineation of a 118-kb interval around interferon-gamma (IFNG) that is involved in male versus female differential susceptibility |
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | Only D12S375 was weakly associated with MS in the ‘low HLA-risk’ group (ie individuals carrying neither DRB1*03 nor DRB1*04 alleles) (P 0.024), especially in men (P 0.049). |
| Mechanism/Pathway | N/A |

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