Basic information of TGFB1 :
| Official Symbol of Gene | TGFB1 |
| Species | Homo sapiens |
| Entrez Gene ID | 7040 |
| Official Full Name | transforming growth factor beta 1 |
| Also known as | CED; LAP; DPD1; TGFB; IBDIMDE; TGFbeta; TGF-beta1 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000105329 MIM:190180; AllianceGenome:HGNC:11766 |
| Map Location | 19q13.2 |
| Variation Type | allel |
| refSNP ID | +869 C |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | Dutch Caucasians |
| Sample Size | 247 MS patients and 194 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 15450129 |
| Year | 2004 |
| Title | Gender-related association between the TGFB1+869 polymorphism and multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | The highest frequency of the TGFB11869 genotype CC was observed in male patients (25.2% vs. 10.0% in controls, p 5 0.004, x2 test), and carriership of TGFB11869 allele C was correspondingly increased in male patients |
| Mechanism/Pathway | N/A |
