Basic information of CD45 :

Official Symbol of Gene	CD45
Species	Homo sapiens
Entrez Gene ID	5788
Official Full Name	protein tyrosine phosphatase receptor type C
Also known as	LCA; LY5; B220; CD45; L-CA; T200; CD45R; GP180; IMD105
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000081237 MIM:151460; AllianceGenome:HGNC:9666
Map Location	1q31.3-q32.1
Variation Type	mutation
refSNP ID	C77G

Sample information of multiple sclerosis:

Detected Sample	N/A
Sample Detail	N/A
Detected Method	PCR-RFLP
Disease	MS
Disease subtype	N/A
Population	Japanese
Sample Size	164 HAM/TSP patients and 108 asymptomatic HTLV-1 carriers inKagoshima (HTLV-1 endemic area in Southern Japan)

Literature information of multiple sclerosis :

Pubmed ID	14641523
Year	2003
Title	A C77G point mutation in CD45 exon 4, which is associated with the development of multiple sclerosis and increased susceptibility to HIV-1 infection, is undetectable in Japanese population

Results of multiple sclerosis :

Risk Type	Disease risk
Main Result	Positive
Result	All 272 subjects showed homozygosity inthe CD45 exon4, suggesting that this mutationis absent or very rare in Japanese population.
Mechanism/Pathway	N/A