Details

Home Details


Basic information of FAS :

Official Symbol of Gene FAS
Species Homo sapiens
Entrez Gene ID 355
Official Full Name Fas cell surface death receptor
Also known as APT1; CD95; FAS1; APO-1; FASTM; ALPS1A; TNFRSF6
Gene Type protein coding
dbXrefs Ensembl:ENSG00000026103 MIM:134637; AllianceGenome:HGNC:11920
Map Location 10q23.31
Variation Type SNP
refSNP ID rs982764a

Sample information of multiple sclerosis:

Detected Sample N/A
Sample Detail N/A
Detected Method PCR
Disease MS
Disease subtype N/A
Population European/Canadian
Sample Size 239 patients

Literature information of multiple sclerosis :

Pubmed ID 17622942
Year 2007
Title Pharmacogenetics of glatiramer acetate therapy for multiple sclerosis reveals drug-response markers

Results of multiple sclerosis :

Risk Type Phenotype risk
Main Result Positive
Result Additionally, we recorded nominally significant associations of response with five other genes, MBP, CD86, FAS, IL1R1 and IL12RB2, which are likely to be involved in glatiramer acetate’s modeof-action, both directly and indirectly.
Mechanism/Pathway N/A