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Basic information of HLA-DRB1 :

Official Symbol of Gene HLA-DRB1
Species Homo sapiens
Entrez Gene ID 3123
Official Full Name major histocompatibility complex, class II, DR beta 1
Also known as SS1; DRB1; HLA-DRB; HLA-DR1B
Gene Type protein coding
dbXrefs Ensembl:ENSG00000196126 MIM:142857; AllianceGenome:HGNC:4948
Map Location 6p21.32
Variation Type polymorphisms
refSNP ID HLA-DRB115

Sample information of multiple sclerosis:

Detected Sample blood
Sample Detail N/A
Detected Method PCR
Disease MS
Disease subtype N/A
Population Canadian and of European
Sample Size 7796 individuals from 1797 MS families

Literature information of multiple sclerosis :

Pubmed ID 20634196
Year 2010
Title Parent-of-origin effects at the major histocompatibility complex in multiple sclerosis

Results of multiple sclerosis :

Risk Type Phenotype risk
Main Result Positive
Result MS-associated allele HLA-DRB115 had a higher female-to-male ratio versus those lacking it (P 5 0.00023).
Mechanism/Pathway N/A