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Basic information of HLA-B :

Official Symbol of Gene HLA-B
Species Homo sapiens
Entrez Gene ID 3106
Official Full Name major histocompatibility complex, class I, B
Also known as AS; HLAB; B-4901
Gene Type protein coding
dbXrefs Ensembl:ENSG00000234745 MIM:142830; AllianceGenome:HGNC:4932
Map Location 6p21.33
Variation Type polymorphisms
refSNP ID B7

Sample information of multiple sclerosis:

Detected Sample blood
Sample Detail N/A
Detected Method PCR
Disease MS
Disease subtype N/A
Population N/A
Sample Size 93 patients with clinically definite MS and 122 healthy controls

Literature information of multiple sclerosis :

Pubmed ID 19232441
Year 2009
Title Gene-environment interactions between HLA B7/A2, EBV antibodies are associated with MRI injury in multiple sclerosis

Results of multiple sclerosis :

Risk Type Phenotype risk
Main Result Positive
Result The HLA B7–A2 haplotype was significantly associated with higher T2-LV and T1-LV and a trend toward lower BPF was observed.
Mechanism/Pathway N/A