Basic information of MX1 :
| Official Symbol of Gene | MX1 |
| Species | Homo sapiens |
| Entrez Gene ID | 4599 |
| Official Full Name | MX dynamin like GTPase 1 |
| Also known as | MX; MxA; IFI78; IFI-78K; lncMX1-215 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000157601 MIM:147150; AllianceGenome:HGNC:7532 |
| Map Location | 21q22.3 |
| Variation Type | SNP |
| refSNP ID | rs2071430 |
Sample information of multiple sclerosis:
| Detected Sample | Peripheral blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | N/A |
| Sample Size | 179 consecutive relapsing patients |
Literature information of multiple sclerosis :
| Pubmed ID | 17126411 |
| Year | 2007 |
| Title | Pharmacogenetics of MXA SNPs in interferon-beta treated multiple sclerosis patients |
Results of multiple sclerosis :
| Risk Type | Treatment risk |
| Main Result | Negative |
| Result | No significant association was found between the MXA genotype at these two SNPs and clinical, MRI and MXA gene expression in MS patients treated with IFN-β therapy. |
| Mechanism/Pathway | The anti-viral activity of MXA could contribute to control of viral infections, which can aggravate the symptoms of MS. |
