Basic information of IGHG1 :
| Official Symbol of Gene | IGHG1 |
| Species | Homo sapiens |
| Entrez Gene ID | 3500 |
| Official Full Name | immunoglobulin heavy constant gamma 1 (G1m marker) |
| Also known as | N/A |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000211896 IMGT/GENE-DB:IGHG1; MIM:147100; AllianceGenome:HGNC:5525 |
| Map Location | 14q32.33 |
| Variation Type | polymorphism |
| refSNP ID | IgG CG1 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | leukocytes |
| Detected Method | N/A |
| Disease | MS |
| Disease subtype | PCPMS,R/RMS |
| Population | N/A |
| Sample Size | 51 MS patients;52 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 8096224 |
| Year | 1993 |
| Title | Immunoglobulin gamma constant gene region polymorphisms in multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | We report here the results of restriction fragment length polymorphisms (RFLP) analysis of the constant gene regions of immunoglobulin gamma (IgG C) 1, 2 and 3 in MS patients and controls, using the restriction enzymes TaqI, PvulI and BstEII. No significant differences were observed, regardless of subgrouping of patients according to clinical disease type or HLA class II phenotype. |
| Mechanism/Pathway | N/A |
