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Basic information of IL1A :

Official Symbol of Gene IL1A
Species Homo sapiens
Entrez Gene ID 3552
Official Full Name interleukin 1 alpha
Also known as IL1; IL-1A; IL1F1; IL1-ALPHA; IL-1 alpha
Gene Type protein coding
dbXrefs Ensembl:ENSG00000115008 MIM:147760; AllianceGenome:HGNC:5991
Map Location 2q14.1
Variation Type SNP
refSNP ID rs1800587

Sample information of multiple sclerosis:

Detected Sample blood
Sample Detail N/A
Detected Method PCR
Disease MS
Disease subtype N/A
Population Turkish
Sample Size 409 MS patients and 256 healthy controls

Literature information of multiple sclerosis :

Pubmed ID 23594042
Year 2013
Title Multiple sclerosis: association with the interleukin-1 gene family polymorphisms in the Turkish population

Results of multiple sclerosis :

Risk Type N/A
Main Result Negative
Result There wasn’t any association between IL-1A 889, IL1RN VNTR and IL-1B +3953 genotypes and MS risk.
Mechanism/Pathway It has been shown that the IL-1A 889 (1/2) polymorphism leads to high expression of IL-1A gene, which may affect progression of MS disease.