Home Details
| Official Symbol of Gene | IL1A |
| Species | Homo sapiens |
| Entrez Gene ID | 3552 |
| Official Full Name | interleukin 1 alpha |
| Also known as | IL1; IL-1A; IL1F1; IL1-ALPHA; IL-1 alpha |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000115008 MIM:147760; AllianceGenome:HGNC:5991 |
| Map Location | 2q14.1 |
| Variation Type | SNP |
| refSNP ID | rs1800587 |
| Detected Sample | blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | Turkish |
| Sample Size | 409 MS patients and 256 healthy controls |
| Pubmed ID | 23594042 |
| Year | 2013 |
| Title | Multiple sclerosis: association with the interleukin-1 gene family polymorphisms in the Turkish population |
| Risk Type | N/A |
| Main Result | Negative |
| Result | There wasn’t any association between IL-1A 889, IL1RN VNTR and IL-1B +3953 genotypes and MS risk. |
| Mechanism/Pathway | It has been shown that the IL-1A 889 (1/2) polymorphism leads to high expression of IL-1A gene, which may affect progression of MS disease. |

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