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Basic information of IL-1RN :

Official Symbol of Gene IL-1RN
Species Homo sapiens
Entrez Gene ID 3557
Official Full Name interleukin 1 receptor antagonist
Also known as DIRA; IRAP; IL1F3; IL1RA; MVCD4; IL-1RN; IL-1ra; IL-1ra3; ICIL-1RA
Gene Type protein coding
dbXrefs Ensembl:ENSG00000136689 MIM:147679; AllianceGenome:HGNC:6000
Map Location 2q14.1
Variation Type SNP
refSNP ID rs 16944

Sample information of multiple sclerosis:

Detected Sample blood
Sample Detail N/A
Detected Method PCR
Disease MS
Disease subtype N/A
Population Turkish
Sample Size 409 MS patients and 256 healthy controls

Literature information of multiple sclerosis :

Pubmed ID 23594042
Year 2013
Title Multiple sclerosis: association with the interleukin-1 gene family polymorphisms in the Turkish population

Results of multiple sclerosis :

Risk Type N/A
Main Result Negative
Result There wasn’t any association between IL-1A 889, IL1RN VNTR and IL-1B +3953 genotypes and MS risk.
Mechanism/Pathway However they suggested that the IL-1Ra VNTR polymorphism might be associated with bout-onset MS subtype.