Basic information of HLA-DRB1 :
| Official Symbol of Gene | HLA-DRB1 |
| Species | Homo sapiens |
| Entrez Gene ID | 3123 |
| Official Full Name | major histocompatibility complex, class II, DR beta 1 |
| Also known as | SS1; DRB1; HLA-DRB; HLA-DR1B |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000196126 MIM:142857; AllianceGenome:HGNC:4948 |
| Map Location | 6p21.32 |
| Variation Type | polymorphism |
| refSNP ID | DRB1*1508 |
Sample information of multiple sclerosis:
| Detected Sample | heparinized blood |
| Sample Detail | lymphocytes |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | MS patients and controls |
| Sample Size | Twenty-three clinically definite MS patients and One hundred forty-six ethnically age- and sex-matched normal individuals |
Literature information of multiple sclerosis :
| Pubmed ID | 12651075 |
| Year | 2003 |
| Title | Evidence for novel DRB1*15 allele association among clinically definite multiple sclerosis patients from Mumbai, India |
Results of multiple sclerosis :
| Risk Type | disease risk |
| Main Result | Positive |
| Result | Further molecular subtyping of HLA-DRB1*15 among the pa tients revealed two novel alleles, DRB1*1506 (20%) and DRB1*1508 (30%), along with the commonly reported DRB1*1501 (50%) for the first time in MS patients that were hitherto unidentified from other parts of India and world as well. |
| Mechanism/Pathway | N/A |
