Details

Home Details


Basic information of HLA-DRB1 :

Official Symbol of Gene HLA-DRB1
Species Homo sapiens
Entrez Gene ID 3123
Official Full Name major histocompatibility complex, class II, DR beta 1
Also known as SS1; DRB1; HLA-DRB; HLA-DR1B
Gene Type protein coding
dbXrefs Ensembl:ENSG00000196126 MIM:142857; AllianceGenome:HGNC:4948
Map Location 6p21.32
Variation Type polymorphism
refSNP ID HLA-DRB1*15

Sample information of multiple sclerosis:

Detected Sample N/A
Sample Detail N/A
Detected Method N/A
Disease MS
Disease subtype N/A
Population from Canada, Sweden, and Norway
Sample Size 4,834 patients with MS, 4,056 controls, and 659 unaffected siblings

Literature information of multiple sclerosis :

Pubmed ID 20018638
Year 2009
Title HLA-DRB1 and month of birth in multiple sclerosis

Results of multiple sclerosis :

Risk Type Disease risk
Main Result Positive
Result Month of birth, HLA-DRB1 genotype, and risk of multiple sclerosis are associated.
Mechanism/Pathway N/A