Basic information of TGFB1 :
| Official Symbol of Gene | TGFB1 |
| Species | Homo sapiens |
| Entrez Gene ID | 7040 |
| Official Full Name | transforming growth factor beta 1 |
| Also known as | CED; LAP; DPD1; TGFB; IBDIMDE; TGFbeta; TGF-beta1 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000105329 MIM:190180; AllianceGenome:HGNC:11766 |
| Map Location | 19q13.2 |
| Variation Type | polymorphism |
| refSNP ID | N/A |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | RR/SPMS,PPMS |
| Population | Northern Ireland |
| Sample Size | 151 patients with RR/SPMS disease, 104 PPMS patients and 159 normal controls |
Literature information of multiple sclerosis :
| Pubmed ID | 10335519 |
| Year | 1999 |
| Title | Lack of association of transforming growth factor (TGF)-beta 1 and beta 2 gene polymorphisms with multiple sclerosis (MS) in Northern Ireland |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | These data indicate that TGF-b1 and b2 genes are not loci inˉuencing MS susceptibility, either RR/SPMS or PPMS, in this population. |
| Mechanism/Pathway | TGF-b is produced by activated T cells, B cells and macrophages |
