Basic information of TGFB2 :
| Official Symbol of Gene | TGFB2 |
| Species | Homo sapiens |
| Entrez Gene ID | 7042 |
| Official Full Name | transforming growth factor beta 2 |
| Also known as | LDS4; G-TSF; TGF-beta2 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000092969 MIM:190220; AllianceGenome:HGNC:11768 |
| Map Location | 1q41 |
| Variation Type | polymorphism |
| refSNP ID | N/A |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | RR/SPMS,PPMS |
| Population | Northern Ireland |
| Sample Size | 130 RR/SPMS patients, 93 PPMS patients and 150 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 10335519 |
| Year | 1999 |
| Title | Lack of association of transforming growth factor (TGF)-beta 1 and beta 2 gene polymorphisms with multiple sclerosis (MS) in Northern Ireland |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | These data indicate that TGF-b1 and b2 genes are not loci inˉuencing MS susceptibility, either RR/SPMS or PPMS, in this population. |
| Mechanism/Pathway | TGF-b is produced by activated T cells, B cells and macrophages |
