Basic information of CCL5 :
| Official Symbol of Gene | CCL5 |
| Species | Homo sapiens |
| Entrez Gene ID | 6352 |
| Official Full Name | C-C motif chemokine ligand 5 |
| Also known as | SISd; eoCP; SCYA5; RANTES; TCP228; D17S136E; SIS-delta |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000271503 MIM:187011; AllianceGenome:HGNC:10632 |
| Map Location | 17q12 |
| Variation Type | polymorphism |
| refSNP ID | RANTES-28G |
Sample information of multiple sclerosis:
| Detected Sample | brain,blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | primary diagnosis of MS from the Human Neurological Research Specimen Bank at Los Angeles Veterans Affairs Medical Center, Los Angeles, CA and (control)older non-Hispanic Caucasian University students |
| Sample Size | 140 postmortem brain samples from subjects with a primary diagnosis of MS, and peripheral blood samples from 216 control subjects. |
Literature information of multiple sclerosis :
| Pubmed ID | 15471370 |
| Year | 2004 |
| Title | RANTES: a genetic risk marker for multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | phenotypics risk |
| Main Result | Positive |
| Result | There was a significant association of the -28G allele with both early onset and longer survival. |
| Mechanism/Pathway | N/A |
