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Basic information of CCL5 :

Official Symbol of Gene CCL5
Species Homo sapiens
Entrez Gene ID 6352
Official Full Name C-C motif chemokine ligand 5
Also known as SISd; eoCP; SCYA5; RANTES; TCP228; D17S136E; SIS-delta
Gene Type protein coding
dbXrefs Ensembl:ENSG00000271503 MIM:187011; AllianceGenome:HGNC:10632
Map Location 17q12
Variation Type polymorphism
refSNP ID RANTES-28C/G

Sample information of multiple sclerosis:

Detected Sample brain,blood
Sample Detail N/A
Detected Method PCR
Disease MS
Disease subtype N/A
Population primary diagnosis of MS from the Human Neurological Research Specimen Bank at Los Angeles Veterans Affairs Medical Center, Los Angeles, CA and (control)older non-Hispanic Caucasian University students
Sample Size 140 postmortem brain samples from subjects with a primary diagnosis of MS, and peripheral blood samples from 216 control subjects.

Literature information of multiple sclerosis :

Pubmed ID 15471370
Year 2004
Title RANTES: a genetic risk marker for multiple sclerosis

Results of multiple sclerosis :

Risk Type disease risk
Main Result Negative
Result MS cases differed from controls showing a significant association with the 403G/A polymorphism,but not the -28C/G.
Mechanism/Pathway N/A