Basic information of TRB :
| Official Symbol of Gene | TRB |
| Species | Homo sapiens |
| Entrez Gene ID | 6957 |
| Official Full Name | T cell receptor beta locus |
| Also known as | TCRB; TRB@ |
| Gene Type | protein coding |
| dbXrefs | AllianceGenome:HGNC:12155 |
| Map Location | 7q34 |
| Variation Type | polymorphism |
| refSNP ID | TCRBV8 |
Sample information of multiple sclerosis:
| Detected Sample | N/A |
| Sample Detail | DNA samples |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | RRMS,CPMS |
| Population | Belgium,Euro-Caucasian |
| Sample Size | 71 unrelated Belgian patients,Sixty-seven randomly selected healthy individuals |
Literature information of multiple sclerosis :
| Pubmed ID | 7911477 |
| Year | 1994 |
| Title | HLA and T-cell receptor polymorphisms in Belgian multiple sclerosis patients: no evidence for disease association with the T-cell receptor |
Results of multiple sclerosis :
| Risk Type | disease risk |
| Main Result | Negative |
| Result | Although the HLA DR2 genotype was significantly associated with MS, no interactive effects were seen with MS, DR2, TCRAC1, TCRBC2 and TCRBV alleles. |
| Mechanism/Pathway | N/A |
