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Basic information of H2 :

Official Symbol of Gene H2
Species Mus musculus
Entrez Gene ID 111364
Official Full Name histocompatibility-2, MHC
Also known as H-2; MHC-II
Gene Type other
dbXrefs N/A
Map Location chromosome: 17
Variation Type polymorphism
refSNP ID H-2s

Sample information of multiple sclerosis:

Detected Sample brain
Sample Detail N/A
Detected Method N/A
Disease EAE
Disease subtype N/A
Population SJL mice
Sample Size N/A

Literature information of multiple sclerosis :

Pubmed ID 6806429
Year 1982
Title Acute autoimmune encephalomyelitis in mice. II. Susceptibility is controlled by the combination of H-2 and histamine sensitization genes

Results of multiple sclerosis :

Risk Type Disease risk
Main Result Positive
Result SJL/J and SWR/J, which are H-2 s and H-2 q, respectively, are susceptible to EAE and sensitive to Bordetella pertussis histamine-sensitizing factor (HSF), which produces a vasoactive amine hypersensitivity.
Mechanism/Pathway N/A