Basic information of HLA-DRB1 :

Official Symbol of Gene	HLA-DRB1
Species	Homo sapiens
Entrez Gene ID	3123
Official Full Name	major histocompatibility complex, class II, DR beta 1
Also known as	SS1; DRB1; HLA-DRB; HLA-DR1B
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000196126 MIM:142857; AllianceGenome:HGNC:4948
Map Location	6p21.32
Variation Type	polymorphism
refSNP ID	HLA-DRB1*15:01

Sample information of multiple sclerosis:

Detected Sample	N/A
Sample Detail	N/A
Detected Method	N/A
Disease	MS
Disease subtype	N/A
Population	N/A
Sample Size	652 patients with MS

Literature information of multiple sclerosis :

Pubmed ID	27244296
Year	2016
Title	Association of HLA Genetic Risk Burden With Disease Phenotypes in Multiple Sclerosis

Results of multiple sclerosis :

Risk Type	Disease risk
Main Result	Positive
Result	A higher HLAGB was associated with younger age at onset and the atrophy of subcortical gray matter fraction in women with relapsing-onset MS (standard β = 1.20 × 101; P = 1.7 × 102 and standard β = 1.67 × 101; P = 2.3 × 104, respectively), which were driven mainly by the HLA-DRB1*15:01 haplotype.
Mechanism/Pathway	N/A