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Basic information of IL6 :

Official Symbol of Gene IL6
Species Homo sapiens
Entrez Gene ID 3569
Official Full Name interleukin 6
Also known as CDF; HGF; HSF; BSF2; IL-6; BSF-2; IFNB2; IFN-beta-2
Gene Type protein coding
dbXrefs Ensembl:ENSG00000136244 MIM:147620; AllianceGenome:HGNC:6018
Map Location 7p15.3
Drug IFN-b treatment
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent N/A
Disease MS

Literature information of multiple sclerosis :

Pubmed ID 12437583
Year 2002
Title Modulation of astrocyte inducible nitric oxide synthase and cytokine expression by interferon beta is associated with induction and inhibition of interferon gamma-activated sequence binding activity

Results of multiple sclerosis :

Result IFN-b inhibits TNF-a, iNOS and IL-6 mRNA expression induced by IL-1/IFN-c. Pre- ()16 h), co- (0 h) and post-treatment (4 h) with IFN-b relative to the timing of IL-1/IFN-c addition show that pretreatment resulted in a greater inhibition of mRNA expression.
Mechanism/pathway human fetal astrocytes revealed that IL-1-induced TNF-a, IL-6, as well as iNOS, are regulated by type-I and type-II IFNs.