Basic information of Ifng :
| Official Symbol of Gene | Ifng |
| Species | Mus musculus |
| Entrez Gene ID | 15978 |
| Official Full Name | interferon gamma |
| Also known as | Ifg; If2f; IFN-g |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSMUSG00000055170 AllianceGenome:MGI:107656 |
| Map Location | 10 D2; 10 66.75 cM |
| Drug | AST treatment |
| Interaction Type | inhibitor |
Sample information of multiple sclerosis:
| Descent | C57BL/6 mice |
| Disease | EAE |
Literature information of multiple sclerosis :
| Pubmed ID | 25150364 |
| Year | 2014 |
| Title | Astragalosides from Radix Astragali benefits experimental autoimmune encephalomyelitis in C57BL /6 mice at multiple levels |
Results of multiple sclerosis :
| Result | However, it decreased IFNγ (p < 0.01), TNFα (p < 0.01) and IL6 (p < 0.05) levels. |
| Mechanism/pathway | Deficiency of p53 increases the severity of EAE possibly by elongating the survival of inflammatory cells in the CNS, therefore, enhancing the production of pro inflammatory cytokines such as IL-6, TNF-α and IFN-γ. |
