Details

Home Details


Basic information of Ifng :

Official Symbol of Gene Ifng
Species Rattus norvegicus
Entrez Gene ID 25712
Official Full Name interferon gamma
Also known as If2f; IFNG2
Gene Type protein coding
dbXrefs Ensembl:ENSRNOG00000007468 AllianceGenome:RGD:2866
Map Location 7q22
Drug pVAXhsp65 Vaccination
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent Lewis rats
Disease EAE

Literature information of multiple sclerosis :

Pubmed ID 20407280
Year 2010
Title Immunization with pVAXhsp65 decreases inflammation and modulates immune response in experimental encephalomyelitis

Results of multiple sclerosis :

Result In addition, it downmodulated IFN-γ and IL-10 production by peripheral lymphoid organs.
Mechanism/pathway This modulatory effect observed on cytokine production could explain the reduced inflammation.