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Basic information of Cxcl10 :

Official Symbol of Gene Cxcl10
Species Mus musculus
Entrez Gene ID 15945
Official Full Name chemokine (C-X-C motif) ligand 10
Also known as C7; IP10; CRG-2; INP10; IP-10; Ifi10; mob-1; Scyb10; gIP-10
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000034855 AllianceGenome:MGI:1352450
Map Location 5 E2; 5 46.57 cM
Drug treatment with ORY-2001
Interaction Type activator

Sample information of multiple sclerosis:

Descent SJL/J mice
Disease EAE

Literature information of multiple sclerosis :

Pubmed ID 35890315
Year 2022
Title Efficacy of Vafidemstat in Experimental Autoimmune Encephalomyelitis Highlights the KDM1A/RCOR1/HDAC Epigenetic Axis in Multiple Sclerosis

Results of multiple sclerosis :

Result only the treatment with ORY-2001 resulted in a significant increase in the production of the pro-inflammatory chemokines IP-10 and MCP-1 induced by MOG35–55
Mechanism/pathway chemokine