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Basic information of Il10 :

Official Symbol of Gene Il10
Species Rattus norvegicus
Entrez Gene ID 25325
Official Full Name interleukin 10
Also known as If2a; IL10X
Gene Type protein coding
dbXrefs Ensembl:ENSRNOG00000004647 AllianceGenome:RGD:2886
Map Location 13q13
Drug pVAXhsp65 Vaccination
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent Lewis rats
Disease EAE

Literature information of multiple sclerosis :

Pubmed ID 20407280
Year 2010
Title Immunization with pVAXhsp65 decreases inflammation and modulates immune response in experimental encephalomyelitis

Results of multiple sclerosis :

Result In addition, it downmodulated IFN-γ and IL-10 production by peripheral lymphoid organs.
Mechanism/pathway This modulatory effect observed on cytokine production could explain the reduced inflammation.