Basic information of Ccl2 :

Official Symbol of Gene	Ccl2
Species	Mus musculus
Entrez Gene ID	20296
Official Full Name	chemokine (C-C motif) ligand 2
Also known as	JE; HC11; MCAF; MCP1; MCP-1; Scya2; Sigje; SMC-CF
Gene Type	protein coding
dbXrefs	Ensembl:ENSMUSG00000035385 AllianceGenome:MGI:98259
Map Location	11 B5; 11 49.82 cM
Drug	treatment with ORY-2001
Interaction Type	activator

Sample information of multiple sclerosis:

Descent	SJL/J mice
Disease	EAE

Literature information of multiple sclerosis :

Pubmed ID	35890315
Year	2022
Title	Efficacy of Vafidemstat in Experimental Autoimmune Encephalomyelitis Highlights the KDM1A/RCOR1/HDAC Epigenetic Axis in Multiple Sclerosis

Results of multiple sclerosis :

Result	only the treatment with ORY-2001 resulted in a significant increase in the production of the pro-inflammatory chemokines IP-10 and MCP-1 induced by MOG35–55
Mechanism/pathway	chemokine