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Basic information of Ifng :

Official Symbol of Gene Ifng
Species Mus musculus
Entrez Gene ID 15978
Official Full Name interferon gamma
Also known as Ifg; If2f; IFN-g
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000055170 AllianceGenome:MGI:107656
Map Location 10 D2; 10 66.75 cM
Drug HSV-1-mediated IL-1 receptor antagonist gene therapy
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent C57Bl/6J mice
Disease EAE

Literature information of multiple sclerosis :

Pubmed ID 16929354
Year 2007
Title HSV-1-mediated IL-1 receptor antagonist gene therapy ameliorates MOG(35-55)-induced experimental autoimmune encephalomyelitis in C57BL/6 mice

Results of multiple sclerosis :

Result Proinflammatory cytokine mRNAs are downregulated in the brain from C57BL/6 EAE mice.
Mechanism/pathway The decreased number of CNS-infiltrating macrophages can determine decreased levels of monocyte-related proinflammatory cytokine mRNA such as IL-1b, IL-6 and TNF-a.