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Basic information of Mbp :

Official Symbol of Gene Mbp
Species Rattus norvegicus
Entrez Gene ID 24547
Official Full Name myelin basic protein
Also known as Mbps
Gene Type protein coding
dbXrefs Ensembl:ENSRNOG00000016516 AllianceGenome:RGD:3054
Map Location 18q12.3
Drug anti-TGF-b treatment
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent Lewis rats
Disease EAE

Literature information of multiple sclerosis :

Pubmed ID 10331018
Year 1999
Title Non-MHC determined resistance of Brown-Norway rats to develop experimental allergic encephalomyelitis is mediated by the endogenous production of transforming growth factor-beta

Results of multiple sclerosis :

Result The anti-TGF-b treatment, however, has no effect on the defect of BN and BN-1L rats to generate a Th1 immune response as illustrated by the absence of IFN-g production upon in vitro restimulation with MBP and EAE peptide.
Mechanism/pathway N/A