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Basic information of Il2 :

Official Symbol of Gene Il2
Species Mus musculus
Entrez Gene ID 16183
Official Full Name interleukin 2
Also known as Il-2
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000027720 AllianceGenome:MGI:96548
Map Location 3 B; 3 18.3 cM
Drug treatment with the MHC variant peptide
Interaction Type activator

Sample information of multiple sclerosis:

Descent C57BL/6 mice
Disease EAE

Literature information of multiple sclerosis :

Pubmed ID 18981103
Year 2008
Title MHC variant peptide-mediated anergy of encephalitogenic T cells requires SHP-1

Results of multiple sclerosis :

Result In contrast, MOG 35–55-specific T cells from me-v/β mice secrete significant amounts of IL-2 (1668 pg/ml) when stimulated with MOG Ag and also following treatment with the MHC variant peptide.
Mechanism/pathway N/A