Basic information of P38 :

Official Symbol of Gene	P38
Species	Mus musculus
Entrez Gene ID	26416
Official Full Name	mitogen-activated protein kinase 14
Also known as	p38; Crk1; Mxi2; p38a; CSBP2; Csbp1; PRKM14; PRKM15; p38MAPK; p38alpha; p38-alpha
Gene Type	protein coding
dbXrefs	Ensembl:ENSMUSG00000053436 AllianceGenome:MGI:1346865
Map Location	17 A3.3; 17 14.85 cM
Drug	IFN-β-treated
Interaction Type	inhibitor

Sample information of multiple sclerosis:

Descent	C57BL/6 mice
Disease	EAE

Literature information of multiple sclerosis :

Pubmed ID	29127843
Year	2018
Title	IFN-β regulates Th17 differentiation partly through the inhibition of osteopontin in experimental autoimmune encephalomyelitis

Results of multiple sclerosis :

Result	IFN-β inhibited downstream inflammatory cytokines through the inhibition of PI3K/AKT/NF-κB axis and p38, JNK-MAPK.
Mechanism/pathway	IFN-β inhibited downstream inflammatory cytokines through the inhibition of PI3K/AKT/NF-κB axis and p38, JNK-MAPK, as well as the regulation of mTOR complexes.