Basic information of NF-kB :

Official Symbol of Gene	NF-kB
Species	Mus musculus
Entrez Gene ID	4790
Official Full Name	nuclear factor kappa B subunit 1
Also known as	KBF1; EBP-1; NF-kB; CVID12; NF-kB1; NFKB-p50; NFkappaB; NF-kappaB; NFKB-p105; NF-kappa-B1; NF-kappabeta
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000109320 MIM:164011; AllianceGenome:HGNC:7794
Map Location	4q24
Drug	IFN-b treatment
Interaction Type	inhibitor

Sample information of multiple sclerosis:

Descent	C57Bl6/SJL
Disease	N/A

Literature information of multiple sclerosis :

Pubmed ID	10845718
Year	2000
Title	Anti-inflammatory action of type I interferons deduced from mice expressing interferon beta

Results of multiple sclerosis :

Result	Analysis of the mechanisms leading to this attenuated inflammatory response showed a decrease in the serum levels of TNF-a and an inhibition of the activation of the transcription factor NF-kB in various tissues.
Mechanism/pathway	systemic administration of IFN-b might influence the response to pro-inflammatory stimuli, in particular through the antagonism of IFN-g signaling.