Basic information of Rora :

Official Symbol of Gene	Rora
Species	Mus musculus
Entrez Gene ID	19883
Official Full Name	RAR-related orphan receptor alpha
Also known as	sg; ROR1; ROR2; ROR3; Nr1f1; nmf267; tmgc26; staggerer; 9530021D13Rik
Gene Type	protein coding
dbXrefs	Ensembl:ENSMUSG00000032238 AllianceGenome:MGI:104661
Map Location	9 C; 9 37.45 cM
Drug	CRAC channel blockers
Interaction Type	inhibitor

Sample information of multiple sclerosis:

Descent	C57BL/6 mice
Disease	EAE

Literature information of multiple sclerosis :

Pubmed ID	24307733
Year	2014
Title	Calcium signaling via Orai1 is essential for induction of the nuclear orphan receptor pathway to drive Th17 differentiation

Results of multiple sclerosis :

Result	The mRNA levels of RORa and RORgt were dramatically reduced, whereas those of T-bet and Foxp3 were not significantly affected.
Mechanism/pathway	Orai1 blockers had a potent anti-inflammatory effect in vivo.