Basic information of Pdgfra :

Official Symbol of Gene	Pdgfra
Species	Rattus norvegicus
Entrez Gene ID	25267
Official Full Name	platelet derived growth factor receptor alpha
Also known as	APDGFR; PDGFACE
Gene Type	protein coding
dbXrefs	Ensembl:ENSRNOG00000002244 AllianceGenome:RGD:3284
Map Location	14p11
Drug	T3/NSCs treatment
Interaction Type	activator

Sample information of multiple sclerosis:

Descent	rat
Disease	EAE

Literature information of multiple sclerosis :

Pubmed ID	26881104
Year	2016
Title	Transplantation of Neural Stem Cells Cotreated with Thyroid Hormone and GDNF Gene Induces Neuroprotection in Rats of Chronic Experimental Allergic Encephalomyelitis

Results of multiple sclerosis :

Result	Furthermore, T3/NSCs and GDNF-T3/NSCs grafting increased the expression of mRNA for PDGFR, GalC, and MBP in lesion areas of brain compared with NSCs grafting, and the expression of mRNA for GalC and MBP in GDNF-T3/NSCs group was higher than that in T3/NSCs group.
Mechanism/pathway	The results suggest that T3/NSCs, especially GDNF-T3/NSCs, more effectively reduce CNS-infiltrating inflammatory cells, thus exerting better effect than NSCs on EAE.