Basic information of Mbp :

Official Symbol of Gene	Mbp
Species	Rattus norvegicus
Entrez Gene ID	24547
Official Full Name	myelin basic protein
Also known as	Mbps
Gene Type	protein coding
dbXrefs	Ensembl:ENSRNOG00000016516 AllianceGenome:RGD:3054
Map Location	18q12.3
Drug	T3/NSCs treatment
Interaction Type	activator

Sample information of multiple sclerosis:

Descent	rat
Disease	EAE

Literature information of multiple sclerosis :

Pubmed ID	26881104
Year	2016
Title	Transplantation of Neural Stem Cells Cotreated with Thyroid Hormone and GDNF Gene Induces Neuroprotection in Rats of Chronic Experimental Allergic Encephalomyelitis

Results of multiple sclerosis :

Result	Furthermore, T3/NSCs and GDNF-T3/NSCs grafting increased the expression of mRNA for PDGFR, GalC, and MBP in lesion areas of brain compared with NSCs grafting, and the expression of mRNA for GalC and MBP in GDNF-T3/NSCs group was higher than that in T3/NSCs group.
Mechanism/pathway	The results suggest that T3/NSCs, especially GDNF-T3/NSCs, more effectively reduce CNS-infiltrating inflammatory cells, thus exerting better effect than NSCs on EAE.