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Basic information of Il17a :

Official Symbol of Gene Il17a
Species Mus musculus
Entrez Gene ID 16171
Official Full Name interleukin 17A
Also known as Il17; Ctla8; IL-17; Ctla-8; IL-17A
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000025929 AllianceGenome:MGI:107364
Map Location 1; 1 A4
Drug treated with rWJSC
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent C57BL/6 mice
Disease EAE

Literature information of multiple sclerosis :

Pubmed ID 28836399
Year 2017
Title Multiple Sclerosis Gene Therapy with Recombinant Viral Vectors: Overexpression of IL-4, Leukemia Inhibitory Factor, and IL-10 in Wharton's Jelly Stem Cells Used in EAE Mice Model

Results of multiple sclerosis :

Result The EAE mice treated with rWJSC showed reduction of Il-17, and brain lesions as well as brain cellular infiltration, in vivo.
Mechanism/pathway gene therapy using anti-inflammatory cytokines can be a promising approach against multiple sclerosis (MS).