Basic information of KLRB1 :

Official Symbol of Gene	KLRB1
Species	Homo sapiens
Entrez Gene ID	3820
Official Full Name	killer cell lectin like receptor B1
Also known as	NKR; CD161; CLEC5B; NKR-P1; NKRP1A; NKR-P1A; hNKR-P1A
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000111796 MIM:602890; AllianceGenome:HGNC:6373
Map Location	12p13.31
Drug	(IFN)-b treatment
Interaction Type	inhibitor

Sample information of multiple sclerosis:

Descent	Scandinavian
Disease	MS

Literature information of multiple sclerosis :

Pubmed ID	21610746
Year	2011
Title	Alterations in KLRB1 gene expression and a Scandinavian multiple sclerosis association study of the KLRB1 SNP rs4763655

Results of multiple sclerosis :

Result	KLRB1 expression decreased significantly (Po0.001) after interferon (IFN)-b treatment.
Mechanism/pathway	KLRB1 was expressed in T and NK cells, and expression mainly decreased in NK cells in patients treated with IFN-b.