Basic information of Bcl2 :

Official Symbol of Gene	Bcl2
Species	Mus musculus
Entrez Gene ID	12043
Official Full Name	B cell leukemia/lymphoma 2
Also known as	Bcl-2; C430015F12Rik; D630044D05Rik; D830018M01Rik
Gene Type	protein coding
dbXrefs	Ensembl:ENSMUSG00000057329 AllianceGenome:MGI:88138
Map Location	1 E2.1; 1 49.76 cM
Drug	treatment with curcumin
Interaction Type	activator

Sample information of multiple sclerosis:

Descent	C57BL/6 mice
Disease	EAE

Literature information of multiple sclerosis :

Pubmed ID	31696502
Year	2019
Title	Curcumin prevents experimental autoimmune encephalomyelitis by inhibiting proliferation and effector CD4+ T cell activation

Results of multiple sclerosis :

Result	After treatment with curcumin, the expression of Bcl-2 was decreased and that of Bax and active caspase-3 was increased.
Mechanism/pathway	The Bcl-2 protein family plays an important role in the induction and control of apoptosis. Bcl2 (an anti-apoptotic protein) and Bax (a pro-apoptotic protein) are the two important members14.