Basic information of Ifng :

Official Symbol of Gene	Ifng
Species	Mus musculus
Entrez Gene ID	15978
Official Full Name	interferon gamma
Also known as	Ifg; If2f; IFN-g
Gene Type	protein coding
dbXrefs	Ensembl:ENSMUSG00000055170 AllianceGenome:MGI:107656
Map Location	10 D2; 10 66.75 cM
Drug	treatment with the KCNN4 blocker
Interaction Type	inhibitor

Sample information of multiple sclerosis:

Descent	C57BL/6 mice
Disease	EAE

Literature information of multiple sclerosis :

Pubmed ID	15770697
Year	2005
Title	Blocking ion channel KCNN4 alleviates the symptoms of experimental autoimmune encephalomyelitis in mice

Results of multiple sclerosis :

Result	Treatment with TRAM-34 reduced the level of proinflammatory cytokines IFN-γ and TNF-a.
Mechanism/pathway	A selective KCNN4 ion-channel blocker, TRAM-34, protected mice from developing EAE, a T cell mediated inflammatory disease, primarily by reducing the level of IFN-γ and TNF-a proteins in the cell infiltrated areas of the central nervous system.