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Basic information of Ifng :

Official Symbol of Gene Ifng
Species Rattus norvegicus
Entrez Gene ID 25712
Official Full Name interferon gamma
Also known as If2f; IFNG2
Gene Type protein coding
dbXrefs Ensembl:ENSRNOG00000007468 AllianceGenome:RGD:2866
Map Location 7q22
Drug IS IL-4 DNA
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent Lewis rats
Disease EAE

Literature information of multiple sclerosis :

Pubmed ID 16564024
Year 2006
Title Intrasplenic electro-transfer of IL-4 encoding plasmid DNA efficiently inhibits rat experimental allergic encephalomyelitis

Results of multiple sclerosis :

Result The MBP-specific expression of IFN-γ from stimulated splenocytes was considerably decreased by the IS IL-4 DNA transfer group both in the preventive and therapeutic experiments while IM transfer had this effect only in the preventive protocol.
Mechanism/pathway Spinal cord inflammation was considerably reduced in the IS IL-4 DNA transfer group.