Basic information of Bax :

Official Symbol of Gene	Bax
Species	Mus musculus
Entrez Gene ID	12028
Official Full Name	BCL2-associated X protein
Also known as	N/A
Gene Type	protein coding
dbXrefs	Ensembl:ENSMUSG00000003873 AllianceGenome:MGI:99702
Map Location	7 B3; 7 29.32 cM
Drug	G-CSF treatment
Interaction Type	activator

Sample information of multiple sclerosis:

Descent	C57BL/6 mice
Disease	EAE

Literature information of multiple sclerosis :

Pubmed ID	27771353
Year	2017
Title	G-CSF treatment promotes apoptosis of autoreactive T cells to restrict the inflammatory cascade and accelerate recovery in experimental allergic encephalomyelitis

Results of multiple sclerosis :

Result	Moreover, G-CSF promoted the G0/G1 to S phase transition of MOG35-55 autoreactive T cells inducing apoptosis and elevating Bax gene expression of apoptosis marker.
Mechanism/pathway	Bax activation leads to mitochondrial dysfunction and cell death. Bax protein forms heterodimers with the apoptosis inhibitor Bcl-2, and the relative levels of these two molecules determine the cell's death.