Details

Home Details


Basic information of Il17a :

Official Symbol of Gene Il17a
Species Mus musculus
Entrez Gene ID 16171
Official Full Name interleukin 17A
Also known as Il17; Ctla8; IL-17; Ctla-8; IL-17A
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000025929 AllianceGenome:MGI:107364
Map Location 1; 1 A4
Drug G-CSF treatment
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent C57BL/6 mice
Disease EAE

Literature information of multiple sclerosis :

Pubmed ID 27771353
Year 2017
Title G-CSF treatment promotes apoptosis of autoreactive T cells to restrict the inflammatory cascade and accelerate recovery in experimental allergic encephalomyelitis

Results of multiple sclerosis :

Result G-CSF therapy reduced pro-inflammatory cytokine IL-1a, TNF-b and NO levels in brain tissue, whereas the anti-inflammatory cytokine IL-4 content was increased.
Mechanism/pathway N/A