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Basic information of Tnf :

Official Symbol of Gene Tnf
Species Mus musculus
Entrez Gene ID 21926
Official Full Name tumor necrosis factor
Also known as DIF; Tnfa; TNF-a; TNFSF2; Tnlg1f; Tnfsf1a; TNFalpha; TNF-alpha
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000024401 AllianceGenome:MGI:104798
Map Location 17 B1; 17 18.59 cM
Drug G-CSF treatment
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent C57BL/6 mice
Disease EAE

Literature information of multiple sclerosis :

Pubmed ID 27771353
Year 2017
Title G-CSF treatment promotes apoptosis of autoreactive T cells to restrict the inflammatory cascade and accelerate recovery in experimental allergic encephalomyelitis

Results of multiple sclerosis :

Result G-CSF therapy reduced pro-inflammatory cytokine IL-1a, TNF-b and NO levels in brain tissue, whereas the anti-inflammatory cytokine IL-4 content was increased.
Mechanism/pathway N/A