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Basic information of Icam1 :

Official Symbol of Gene Icam1
Species Mus musculus
Entrez Gene ID 15894
Official Full Name intercellular adhesion molecule 1
Also known as CD54; Ly-47; Icam-1; MALA-2
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000037405 AllianceGenome:MGI:96392
Map Location 9 A3; 9 7.69 cM
Drug Sativex
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent SJL/J mice
Disease EAE

Literature information of multiple sclerosis :

Pubmed ID 25857324
Year 2015
Title A Sativex() -like combination of phytocannabinoids as a disease-modifying therapy in a viral model of multiple sclerosis

Results of multiple sclerosis :

Result Sativex also reduced the expression of VCAM-1 and ICAM-1.
Mechanism/pathway Sativex may restrict the permissiveness of immune cell infiltration into the CNS parenchyma.