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Basic information of Ifng :

Official Symbol of Gene Ifng
Species Mus musculus
Entrez Gene ID 15978
Official Full Name interferon gamma
Also known as Ifg; If2f; IFN-g
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000055170 AllianceGenome:MGI:107656
Map Location 10 D2; 10 66.75 cM
Drug Sativex
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent SJL/J mice
Disease EAE

Literature information of multiple sclerosis :

Pubmed ID 25857324
Year 2015
Title A Sativex() -like combination of phytocannabinoids as a disease-modifying therapy in a viral model of multiple sclerosis

Results of multiple sclerosis :

Result Sativex decreased microglial activity, down-regulated the expression of proinflammatory cytokines and up-regulated arginase-1 (Arg-1) and IL-10 in the spinal cord of TMEV-infected mice
Mechanism/pathway Sativex could act as an immunomodulator, not only limiting the inflammation in TMEV-IDD mice but also promoting an anti-inflammatory environment.