Basic information of Arg1 :

Official Symbol of Gene	Arg1
Species	Mus musculus
Entrez Gene ID	11846
Official Full Name	arginase, liver
Also known as	AI; PGIF; Arg-1
Gene Type	protein coding
dbXrefs	Ensembl:ENSMUSG00000019987 AllianceGenome:MGI:88070
Map Location	10; 10 A4
Drug	Sativex
Interaction Type	activator

Sample information of multiple sclerosis:

Descent	SJL/J mice
Disease	EAE

Literature information of multiple sclerosis :

Pubmed ID	25857324
Year	2015
Title	A Sativex() -like combination of phytocannabinoids as a disease-modifying therapy in a viral model of multiple sclerosis

Results of multiple sclerosis :

Result	Sativex decreased microglial activity, down-regulated the expression of proinflammatory cytokines and up-regulated arginase-1 (Arg-1) and IL-10 in the spinal cord of TMEV-infected mice
Mechanism/pathway	Sativex could act as an immunomodulator, not only limiting the inflammation in TMEV-IDD mice but also promoting an anti-inflammatory environment.