Basic information of myelin genes :

Official Symbol of Gene	myelin genes
Species	Mus musculus
Entrez Gene ID	N/A
Official Full Name	N/A
Also known as	N/A
Gene Type	N/A
dbXrefs	N/A
Map Location	N/A
Drug	Gemfibrozil
Interaction Type	activator

Sample information of multiple sclerosis:

Descent	PPAR-α(-/-) and PPAR-β(-/-) mice
Disease	experimental autoimmune encephalomyelitis

Literature information of multiple sclerosis :

Pubmed ID	22879602
Year	2012
Title	Gemfibrozil, a lipid-lowering drug, increases myelin genes in human oligodendrocytes via peroxisome proliferator-activated receptor-β

Results of multiple sclerosis :

Result	Furthermore, gemfibrozil treatment also led to the recruit ment of PPAR- to the PLP promoter in vivo in the spinal cord of experimental autoimmune encephalomyelitis mice and suppres sion of experimental autoimmune encephalomyelitis symptoms in PLP-T cell receptor transgenic mice.
Mechanism/pathway	Gemfibrozil, an FDA-approved drug for hyperlipidemia, stimulates the expression of myelin genes in primary human oligodendroglia via PPAR-β.