Basic information of Pparg :

Official Symbol of Gene	Pparg
Species	Mus musculus
Entrez Gene ID	19016
Official Full Name	peroxisome proliferator activated receptor gamma
Also known as	Nr1c3; PPARgamma; PPAR-gamma; PPARgamma2; PPAR-gamma2
Gene Type	protein coding
dbXrefs	Ensembl:ENSMUSG00000000440 AllianceGenome:MGI:97747
Map Location	6 E3; 6 53.41 cM
Drug	PPARγ agonists
Interaction Type	activator

Sample information of multiple sclerosis:

Descent	C57BL/6 mice
Disease	EAE

Literature information of multiple sclerosis :

Pubmed ID	12112074
Year	2002
Title	Peroxisome proliferator-activated receptor-gamma agonists prevent experimental autoimmune encephalomyelitis

Results of multiple sclerosis :

Result	Clinical symptoms were reduced by two other PPAR agonists,suggesting a role for PPAR activation in protective effects.
Mechanism/pathway	Ligands of the peroxisome proliferator-activated recep tor (PPAR) exert anti-inflammatory effects on glial cells,reduce proliferation and activation of T cells, and induce myelin gene expression.