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Basic information of IL-10 :

Official Symbol of Gene IL-10
Species Mus musculus
Entrez Gene ID 16153
Official Full Name interleukin 10
Also known as CSIF; If2a; Il-10
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000016529 AllianceGenome:MGI:96537
Map Location CSIF; If2a; Il-10
Drug NT-3-NSCs and NT-3/IL-10-NSCs treatment
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent C57BL/6 mice
Disease EAE

Literature information of multiple sclerosis :

Pubmed ID 27203442
Year 2016
Title Neural Stem Cells Engineered to Express Three Therapeutic Factors Mediate Recovery from Chronic Stage CNS Autoimmunity

Results of multiple sclerosis :

Result These results indicate that IL-10 in the cocktail plays an important role in the inhibition of CNS inflammatory infiltration.
Mechanism/pathway IL-10, an effective immunoregulatory cytokine.