Basic information of Jag1 :

Official Symbol of Gene	Jag1
Species	Mus musculus
Entrez Gene ID	16449
Official Full Name	jagged 1
Also known as	Htu; Ozz; ABE2; Ser-1; Gena228; Gsfabe2
Gene Type	protein coding
dbXrefs	Ensembl:ENSMUSG00000027276 AllianceGenome:MGI:1095416
Map Location	2 F3; 2
Drug	Jagged1 treatment
Interaction Type	activator

Sample information of multiple sclerosis:

Descent	C57B6 mice
Disease	MS

Literature information of multiple sclerosis :

Pubmed ID	18030350
Year	2007
Title	A network analysis of the human T-cell activation gene network identifies JAGGED1 as a therapeutic target for autoimmune diseases

Results of multiple sclerosis :

Result	In vitro treatment with a Jagged1 agonist peptide modulated the T-cell activation network in PBMCs from patients with MS.
Mechanism/pathway	Our results suggested that the Jagged1-Notch pathway modulates Th1 function.